Adrenal Cancer Treatment

Specialized care for adrenocortical carcinoma and pheochromocytoma with advanced chemotherapy, targeted therapy, and comprehensive endocrine management.

7+
Years Experience
150+
Adrenal Cancer Patients
82%
Treatment Response

Advanced Adrenal Cancer Treatment

Expert management of adrenocortical carcinoma and pheochromocytoma with mitotane therapy, chemotherapy combinations, and comprehensive endocrine care. We specialize in hormone-secreting tumors and metastatic disease.

Diagnosis & Staging

Advanced Imaging

CT, MRI, and PET-CT for accurate staging and assessment of local invasion and metastases.

Hormone Testing

Comprehensive endocrine evaluation including cortisol, aldosterone, catecholamines, and steroid profiling.

Pathological Analysis

Core needle biopsy, immunohistochemistry, and Weiss criteria for adrenocortical carcinoma grading.

Treatment Options

Mitotane Therapy

First-line treatment for adrenocortical carcinoma with mitotane monotherapy or combination regimens.

  • Mitotane monotherapy
  • Mitotane + EDP (Etoposide + Doxorubicin + Cisplatin)
  • Mitotane + Streptozotocin
  • Maintenance mitotane

Targeted Therapy

Precision medicine for adrenocortical carcinoma with novel targeted agents and clinical trials.

  • Linsitinib (OSI-906)
  • Cabozantinib (Cabometyx)
  • Clinical trial agents
  • Combination therapies

Endocrine Management

Comprehensive management of hormone-secreting tumors and endocrine complications.

  • Cortisol replacement therapy
  • Blood pressure management
  • Electrolyte monitoring
  • Symptom control

Common Symptoms

Hormone Excess

High blood pressure, weight gain, diabetes, facial redness, or hypokalemia from cortisol/aldosterone excess.

Episodic Symptoms

Headache, palpitations, sweating (pheochromocytoma); anxiety and tremors during episodes.

Mass Effect

Abdominal fullness, flank pain, or incidental adrenal mass on imaging.

Risk Factors

Genetic Syndromes

Li-Fraumeni, MEN1, Lynch, NF1; family history of endocrine tumors.

Prior Radiation

Previous abdominal radiation exposure increases risk in some patients.

Other Factors

Adrenal incidentalomas, long-standing endocrine disorders warrant evaluation.

Follow-up Care